Dr. M. Ehsan Karim and the Epi-OER team are developing an OER to enhance methodological training in epidemiology by integrating open-source data, R software, and interactive learning tools into the SPPH 604 course. This comprehensive resource includes an interactive open textbook, real-world data analysis exercises, and self-paced learning modules, making advanced epidemiological methods more accessible and strengthening analytical expertise in health research.